Clontech
login | register | order now | view cart | feedback
Products
cDNA Synthesis & Library Construction


Products >  cDNA_Synthesis_and_Library_Construction >  Oligo_Modification >  Label-ON_Reagents

Oligo Modification—Label-ON Reagents

Label-ON Reagents provide an efficient way to directly label oligonucleotides with various reporter molecules (1–4). All Label-ON Reagents possess the patented 2-aminobutyl-1,3-propanediol (ABPD) backbone, which offers the following distinct labeling advantages:

  • Multiple labels can be incorporated because Label-ON Phosphoramidites do not truncate chain elongation at the 5' terminus.
  • Natural 3-carbon internucleotide phosphodiester distance is maintained, providing better hybridization and annealing properties than those obtained with other labeling methods.
  • Attached label is separated from the phosphodiester connection point to reduce steric hindrance. The ABPD backbone has a 7-atom spacer arm that separates the label from the connection point.
  • Label incorporation can be easily measured by standard trityl cation assays because all Label-ON Phosphoramidites possess a dimethoxytrityl (DMT) protected hydroxyl group.

The Uni-Link AminoModifier allows you to directly incorporate a primary amine onto the 5' end of an oligonucleotide using automated synthesis. All Label-ON reagents are provided with a User Manual.

Please inquire about bulk orders or custom synthesis requests at tech@clontech.com.

 
 
Products
Cat. # Product Contents Size Price Units Select
635703 Uni-Link™ AminoModifier 100 mg $264.00
 

 

 
 

Takara Bio USA is a Takara Bio Company © 2018 Privacy Policy | Terms & Conditions | Terms of Use