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Transfection & Cell Culture

Products >  Transfection_and_Cell_Culture >  RNA_Transfection >  Xfect_RNA_Transfection_Reagent

Xfect RNA Transfection Reagent for siRNA, sgRNA, microRNA, and mRNA

Xfect RNA Transfection Reagent is a complete system for highly efficient transfection of mammalian cells with all types of RNA. Transfection with messenger RNA allows for rapid gene expression, without the risk of genomic integration that comes from transfection with DNA. While most transfection reagents can be harmful to your cells, the Xfect RNA Transfection Reagent has very low cytotoxicity. The reagent can also efficiently deliver single guide RNAs (sgRNA) for CRISPR/Cas9-mediated gene editing. This reagent creates biodegradable nanoparticles when combined with RNA, enabling efficient transfection of mammalian cells without any of the damaging side-effects.

The Xfect RNA Transfection Reagent is compatible with all types of RNA, including mRNA, single guide RNA (sgRNA), microRNA, and siRNA. The protocol is simple, and transfections can be carried out entirely in the presence of serum.

When used in conjunction with the Xfect Transfection Reagent, the Xfect RNA Transfection Reagent can be used for efficient cotransfection of mammalian cells with both DNA and RNA.

  At-A-Glance   Documents   Images & Data   Resources


  • Single reagent for transfection with messenger RNA (mRNA), guide RNA (sgRNA), microRNA (miRNA) ,and siRNA
  • High transfection efficiency and very low cytotoxicity in cell lines and primary cells
  • Simple, serum-compatible protocol
  • Complete system that includes all components necessary for transfection


  • RNA transfection
  • Knockdown of gene expression using siRNA
  • Transient transfection with mRNA transcripts, without genomic integration
  • Knockout of gene expression using CRISPR/Cas9-mediated gene editing

Additional Information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

Cat. # Product Contents Size Price License Units Select
631450 Xfect™ RNA Transfection Reagent 1.2 mL $225.00 License Statements


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