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Products >  Stem_Cell_Research >  Cells >  Human_Stem_Cell_Derived_Beta_Cells

Pancreatic Beta Cells Derived from Human Induced Pluripotent Stem Cells

The Cellartis hiPS Beta Cells (from ChiPSC12) Kit contains beta cells generated in vitro using a standardized protocol that mimics embryonic development. These cells secrete high amounts of insulin and C-peptide, and show substantial protein expression of insulin/C-peptide, MAFA, NKX6.1, PDX1, and UCN3. The complete kit is an excellent research tool for investigating beta-cell function, diabetes/disease modeling, and compound screening for insulin secretion and regulation.

Cellartis beta cells have been differentiated from our ChiPSC12 line of human induced pluripotent stem (iPS) cells, dissociated into a single-cell suspension, and frozen in vials. The kit contains beta cells, coating substrate, basal media, and a supplement.

  At-A-Glance   Documents   Images & Data   Resources

Features

  • Protein expression of insulin/C-peptide, MAFA, NKX6.1, PDX1, and UCN3
  • Insulin and C-peptide secretion
  • Derived with a protocol that mimics embryonic development
  • Provide reproducible and biologically relevant data

Applications

  • Disease modeling for diabetes
  • Compound screening for insulin secretion and regulation
  • Beta-cell functionality
  • GSIS (glucose-stimulated insulin secretion) analysis
  • Incretin response studies
  • Autoimmune beta-cell destruction
  • Pancreatitis and beta-cell function
  • Transdifferentiation

Components

  • 1 vial (4.8 x 106 viable cells) of Cellartis hiPS Beta Cells (from ChiPSC12)
  • 11 vials (360 µl/vial) of Cellartis Beta Cell Supplement
  • 1 tube (4 ml) of Cellartis Beta Cell Coating
  • 1 bottle (160 ml) of Cellartis Beta Cell Basal Medium
  • 1 bottle (30 ml) of Cellartis Beta Cell Basal Medium 2

Additional Product Information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.


 
 
Products
New Cat. # Product Contents Size Price License Units Select
Y10100 Cellartis® hiPS Beta Cells (from ChiPSC12) Kit 1 Kit $1,421.00 License Statements
 

 

 
 

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