Co-Immunoprecipitation (Co-IP) Kit for Nuclear Extracts
Co-immunoprecipitation (Co-IP) is used to pull down an entire complex of intact proteins in order to identify unknown members of the complex.
The EpiXplore Nuclear Co-Immunoprecipitation (Co-IP) Kit is designed to evaluate protein-protein complexes from nuclear extracts. The kit utilizes specially formulated magnetic Protein G beads, which have been optimized to maximize signal-to-noise ratios, and includes cytoplasmic and nuclear lysis buffers to fractionate nuclear proteins. Enzymatic treatment of nuclear extracts enables release of proteins from genomic DNA. The included wash buffers enable flexibility for detection of strong or weak protein-protein interactions.