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Nucleic Acid Purification

Products >  Nucleic_Acid_Purification >  RNA >  Total_RNA_from_Cells_and_Tissues >  RNA_Plus_XS_Miniprep

NucleoSpin RNA Plus XS—Fast, Efficient RNA Isolation from the Smallest Samples

The NucleoSpin RNA Plus XS kit is designed to purify RNA from very small amounts of a wide variety of cell and tissue types, as well as single mammalian cells. This kit includes the NucleoSpin gDNA Removal Column XS, a spin column that quickly and effectively removes genomic DNA without the need for DNase digestion.

  At-A-Glance   Documents


  • Developed for extra-small samples and single-cell analysis
  • gDNA removal column eliminates the need for time-consuming DNA digestion
  • Novel lysis buffer does not contain mercapthoethanol or TCEP


  • RNA isolation from small amounts of cultured cells, human/animal tissue
  • RNA from samples stored in RNAlater
  • Typical downstream applications: real-time RT-PCR, Northern blotting, primer extension, array technology, RNase protection assays, RNA-sequencing

Product Overview

Technology Silica membrane
Format Two columns: 
XS column for DNA removal
XS column for RNA isolation
Starting material Cultured cells (1–105)
Human/animal tissue (<5 mg)
Typical yield HeLa cells (105): 0.5–2 μg
HeLa cells (101): 0.05–0.2 ng
Mouse liver (0.5 μg): 2.5–8 ng
Mouse brain (0.5 μg): 0.1–0.5 ng
Elution volume 5–30 μl
A260/A280 1.9–2.2
Preparation time 18 min/6 preps
Binding capacity 110 μg

Additional product information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.

New Cat. # Product Contents Size Price Units Select
740990.10 NucleoSpin® RNA Plus XS 10 Preps $89.00
740990.50 NucleoSpin® RNA Plus XS 50 Preps $381.00
740990.250 NucleoSpin® RNA Plus XS 250 Preps $1,678.00



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