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Nucleic Acid Purification

Products >  Nucleic_Acid_Purification >  Accessories >  Equipment_24-Vacuum

Vacuum processing of nucleic acid purification columns—NucleoVac 24 Vacuum Manifold

The NucleoVac 24 Vacuum Manifold allows the parallel processing of silica columns for nucleic acid purification by vacuum. The silica columns (e.g., NucleoSpin and NucleoSnap columns) can be attached to the upper Luer openings of the vacuum manifold. The binding and washing steps of the NucleoSpin or NucleoSnap procedures are carried out by vacuum instead of centrifugation, enabling time-saving procedures (NucleoSpin products) and processing of large sample volumes (NucleoSnap products).

The NucleoVac 24 Vacuum Manifold Procedure

Close the lower threaded opening of the NucleoVac 24 Vacuum Manifold (see manifold diagram) with the rubber closing plug (1). Screw in the tubing connection (2) in the upper opening (3) manually. Do not use a wrench as the conical screw thread might crack if the connection is over-tightened. Attach the vacuum tubing (not included).

For processing NucleoSpin (4) or NucleoSnap columns with the NucleoVac 24 Vacuum Manifold (see processing diagram), insert NucleoSpin or NucleoSnap columns into the Luer openings (5)(a). To avoid cross-contamination, we recommend using disposable NucleoVac Mini Adapters (6)(b). For processing samples with different flow rates (e.g., large volume samples), we recommend using NucleoVac Stopcocks (7)(c) for maintaining constant vacuum pressure throughout the entire procedure. Close unused Luer openings with Luer plugs (8)(d).

  At-A-Glance   Documents   Images & Data


  • Time-saving processing of 24 samples in parallel
  • Parallel processing of silica columns (e.g., NucleoSpin and NucleoSnap columns) for nucleic acid purification
  • Fast processing of large sample volumes


  • Nucleic acid purification by vacuum

Product Overview

Material Polypropylene
Number of Samples 1–24
Waste Capacity ≤900 ml
Column Compatibility NucleoSpin, NucleoSnap

NucleoVac 24 and Accessory Product Specifications

Product Name Size Specification Cat. #
NucleoVac 24 Vacuum Manifold1
NucleoVac 24 Vacuum Manifold, 24 NucleoVac Mini Adapters, 24 Luer plugs, 2 tubing connections, 1 closing plug740299
NucleoVac Mini Adapters100 eachLuer adapters for connecting NucleoSpin or NucleoSnap columns to NucleoVac 24
Vacuum Manifold
NucleoVac Stopcocks24
Stopcocks for handling different flow rates of NucleoSpin and NucleoSnap columns on a NucleoVac 24 Vacuum Manifold740298.24

Cat. # Product Contents Size Price Units Select
740297.100 NucleoVac Mini Adapter 100 Each $87.00
740298.24 NucleoVac Stopcocks 24 Each $125.00
740299 NucleoVac 24 Vacuum Manifold Each $236.00



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