Because Clontech's Tet-On and Tet-Off Systems are extremely sensitive, even “antibiotic-free” fetal bovine serum that has no negative effect on cell growth may still exhibit enough activity to alter Tet-regulated gene expression. You can be confident that Tet System Approved FBS will not adversely affect Tet-On or Tet-Off experiments.
*Testing for the presence of tetracyclines in fetal or calf serum is not equivalent to the highly sensitive functional testing that is performed on Clontech Tet System Approved FBS.
Four Versions of Tet System Approved Fetal Bovine Serum Are Available
- All sera are subjected to the same rigorous testing to ensure full inducibility.
- Each lot of our ES Cell Qualified serum undergoes additional tests to confirm expected results regarding cell size, cell morphology, colony forming ability, pluripotency, maintenance of ESC cells in the undifferentiated state, and the potential of ESCs to differentiate into embryoid bodies.
A premium cell culture serum that is collected in the United States.
A premium serum that is collected in Australia.
ES Cell Qualified FBS
A premium serum that is collected in the United States and qualified for use in embryonic stem cells.
Tet System Approved FBS
Is an economical alternative obtained from non-US, USDA-approved sources.