Put a switch on it…
Imagine turning on your specific signaling pathway on demand, and independently of upstream signals! iDimerize Systems are powerful technologies for creating conditional alleles that can be activated within seconds of adding a small molecule ligand.
Take complete control
- Induce protein-protein interactions or protein translocation
- Isolate one pathway from a complex signaling network
- Activate conditional alleles at any developmental time point
- Eliminate toxicity and/or cross-talk of constitutive models
- Study phenotype maintenance & reversibility