Regulatory associated protein of mTOR, complex 1 (Raptor) is encoded by the RPTOR gene. It is involved in the control of the mammalian target of rapamycin (mTOR) and is a subunit of mTORC1. Raptor binds to mTOR kinase and functions as a scaffold for recruiting mTORC1 substrates. It also associates with eukaryotic translation initiation factor 4E-binding protein 1 (EIF4BP1) and ribosomal protein S6 kinase (S6K1). Raptor negatively regulates mTOR kinase but positively regulates S6K1. Raptor also interacts with unc-51-like kinase 1 (ULK1) in a nutrient-dependent manner. Raptor is also known as p150 target of rapamycin (TOR)-scaffold protein, KIAA1303, KOG1, and Mip1.
These products are affinity-purified IgG antibodies that recognize human Raptor protein. The antibodies were raised in rabbit using synthetic peptides and can be used for Western blot (WB) detection or immunoprecipitation (IP) of human Raptor protein.