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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Miscellaneous >  Primary_Antibodies_L-Z >  Podocin

Anti-Human Podocin Rabbit IgG Antibody

Podocin is a component of the slit diaphragm of podocytes, cells that are located in the Bowman's capsule in the kidneys. In humans, it is encoded by the NPHS2 gene. In the glomerulus, blood is filtered through the slit diaphragms before passing into nephrons. Podocin is one of several proteins that control glomerular permeability. It acts as a linker between the plasma membrane and the cytoskeleton. Mutations in the NPHS2 gene cause autosomal recessive steroid-resistant nephrotic syndrome (SRNS), a disease that rapidly progresses to end-stage renal disease (ESRD). Podocin has also been implicated in the development of other nephropathies, such as focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Podocin is also known as nephrosis 2, idiopathic, steroid-resistant (podocin); PDCN, and SRN1.

This product is an affinity-purified IgG antibody that recognizes human podocin protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human podocin protein.

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  • Cat.#: 29040A, 29040B
  • Target Name: Human podocin protein
  • Antigen: Human podocin synthetic peptide
  • Application: WB, IHC, IP
  • Specificity: Cross-reacts with rat and mouse podocin
  • Target Entrez Gene ID: 7827


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.1 µg/mL
  • Immunohistochemical techniques: 1–2 µg/mL
  • Immunoprecipitation: 1–2 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Nephrosis 2, idiopathic, steroid-resistant (podocin); NPHS2, PDCN, SRN1

Cat. # Product Contents Size Price Units Select
29040A Anti-Human Podocin Rabbit IgG Affinity Purify 10 ug $125.00
29040B Anti-Human Podocin Rabbit IgG Affinity Purify 100 ug $545.00



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