Lecithin retinol acyltransferase (LRAT) is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is essential for the retinoid cycle in retinal photopigmentation and to metabolize vitamin A in the liver. Mutations in the LRAT gene have been associated with early-onset severe retinal dystrophy. LRAT is also known as phosphatidylcholine--retinol O-acyltransferase, LCA14, AI449251, and 1300010A18Rik.
This product is an affinity-purified IgG antibody that recognizes mouse LRAT protein. The antibody was raised in rabbit using a synthetic peptide, and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of mouse LRAT protein.