Hepatic triglyceride lipase or HTGL is encoded by the LIPC gene and is expressed primarily in the liver. HTGL, also known as hepatic lipase, is a lipolytic enzyme expressed by hepatocytes and plays a role in lipoprotein metabolism as well as the hydrolysis of triglycerides (TGs), phospholipids, intermediate-density lipoproteins (IDLs), and high-density lipoproteins (HDLs). HTGL has a high affinity for heparin, and measurement of HTGL in plasma is typically performed after intravenous injection with heparin (post-heparin plasma).
This kit is a solid phase sandwich ELISA that uses two highly specific antibodies to detect human HTGL (LIPC); one is precoated on the ELISA plate, and the other is HRP-conjugated. This kit can be used to measure human HTGL in post-heparin plasma collected with EDTA in cell culture supernatant.