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Cell Biology & Epigenetics


Products >  Cell_Biology_and_Epigenetics >  Metabolic_Diseases >  DPP4

Dipeptidyl Peptidase-4 Detection—DPP4 ELISA

This kit is a solid-phase sandwich ELISA that uses two antibodies that are highly specific to human Dipeptidyl peptidase-4 (DPP4); one is pre-coated on the ELISA plate and the other is HRP-conjugated. This assay kit can be used to measure human DPP4 protein in serum, EDTA-plasma, urine, cerebrospinal fluid, and cell culture supernatants.

DPP4 (also known as CD26) is a transmembrane glycoprotein receptor that is involved in T cell activation. In addition, DPP4 functions as a serine exopeptidase to regulate various physiological processes by cleavage of substrates including hormones, growth factors, chemokines, and incretins. One DPP4 target is glucagonlike peptide-1 (GLP-1), an incretin that regulates insulin secretion; recently, DPP4 inhibitors have been developed for the treatment of diabetes. In addition to regulating glucose metabolism, it is thought that DPP4 plays a role in tumor biology, and its expression is used as a marker for various cancers.

  At-A-Glance   Documents

Features

  • Capable of measuring human DPP4 protein
  • Sensitivity: 8.58 pg/ml

Applications

  • Measuring human DPP4 protein in serum, EDTA-plasma, urine, cerebrospinal fluid, and cell culture supernatants

Performance

  • Range of assay: 125–8000 pg/ml
  • Assay sensitivity: 8.58 pg/ml
  • Assay duration: Approximately 2.0 hours
  • Test specimen type: Serum, EDTA-plasma, urine, cerebrospinal fluid, cell culture supernatants
  • Specificity: Shows ≤0.1% cross-reactivity with mouse and rat DPP4
  • Sample volume per well: 100 µl

Additional Information

Please refer to technical documents under the Documents tab for storage conditions, product components, and technical specifications.


 
 
Products
Cat. # Product Contents Size Price Units Select
27789A Human DPP4/CD26 Assay Kit - IBL 96-Well $709.00
 

 

 
 

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