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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Cytokines >  MCP-1

MCP-1 Detection

Monocyte chemoattractant protein-1 (MCP-1) is a 76-amino acid cytokine that belongs to the CC chemokine subfamily. MCP-1 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. MCP-1 is implicated in several types of chronic inflammatory diseases, such as psoriasis, rheumatoid arthritis, nephritis, and atherosclerosis.

Alternate names for MCP-1 include macrophage/monocyte chemotactic and activating factor (MCAF), chemokine (C-C motif) ligand 2 (CCL2), small inducible cytokine A2, SCYA2, HC11, GDCF-2, SMC-CF, monocyte secretory protein JE, and monocyte chemotactic protein.

ELISAs for MCP-1 Detection

The Rat MCP-1 Assay Kit is a solid-phase sandwich ELISA using two antibodies that are highly specific to recombinant and native rat MCP-1 protein; one is precoated on the ELISA plate and the other is HRP-conjugated. This kit can be used to measure soluble rat MCP-1 protein in serum, urine, or cell culture supernatants.

Antibodies for MCP-1 Detection

The MCP-1 antibody products are affinity-purified IgG antibodies that recognize rat MCP-1 protein. The antibodies were raised in mouse (Cat. #10121A/B) or rabbit (Cat. #18371A/B) using recombinant protein (Cat. #10121A/B) or synthetic peptide (Cat. #18371A/B); these antibodies can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of rat MCP-1 protein.

  At-A-Glance   Documents   Images & Data
Cat. #
(Clone) and Source
Rabbit IgG

Detect: HRP
Mouse IgG MoAb
≤0.1% cross-reactivity with rat GRO/CINC-1, -2 alpha, -2 beta, -3, Rantes, MIP-1 alpha, IL-1 beta,
IL-6, and Leptin
MCP-110121A, BWBRat(MB10)
Mouse IgG1 MoAb
18371A, BIHC
Rabbit IgG
Cross-reacts with human and mouse MCP-1

Additional Information

Please see a product's User Manual and Data Sheet for information about storage conditions, product components, and technical specifications. Please see the User Manual to determine kit components. User Manuals and Data Sheets are located under the Documents tab.

Cat. # Product Contents Size Price Units Select
17176A Rat MCP-1 Assay Kit - IBL 96-Well $664.00
10121A Anti-Rat MCP-1 (MB10) Mouse IgG MoAb 10 ug $125.00
10121B Anti-Rat MCP-1 (MB10) Mouse IgG MoAb 100 ug $545.00



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