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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Cell_Adhesion_and_Extracellular_Matrix >  Occludin

Anti-Rat Occludin (1A8) Mouse IgM MoAb

Occludin is an integral membrane protein, encoded by the OCLN gene, that is located at tight junctions. Tight junctions act as a physical barrier to prevent solutes and water from passing freely through the paracellular space. Occludin is also known as BLCPMG. It is known to interact with several cytoplasmic proteins via its C terminus, while its extracellular loops are thought to be involved in the regulation of paracellular permeability and cell adhesion. When occludin is expressed in cells that lack tight junctions, it is able to induce cell adhesion. Mutations in the OCLN gene are associated with an autosomal recessive neurologic disorder known as band-like calcification with simplified gyration and polymicrogyria (BLC-PMG).

This product is an affinity-purified IgG antibody that recognizes rat occludin protein. The antibody was raised in mouse using recombinant occludin and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of rat, human, and dog occludin protein.

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  • Cat.#: 10345A, 10345B
  • Target Name: Rat occludin protein
  • Antigen: Rat occludin recombinant protein
  • Specificity: Cross-reacts with human and dog occludin
  • Application: WB, IHC
  • Target Entrez Gene ID: 83497


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 0.1–0.5 µg/mL
  • Immunohistochemical techniques: 0.5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 50 µg/mL).

Alternative names


Cat. # Product Contents Size Price Units Select
10345A Anti-Rat Occludin (1A8) Mouse IgM MoAb 5 ug $125.00
10345B Anti-Rat Occludin (1A8) Mouse IgM MoAb 50 ug $545.00



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