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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Cancer_and_Inflammation >  TSC1_Hamartin

Anti-Human TSC1/Hamartin (T1149) Rabbit IgG Antibody

The tuberous sclerosis 1 (TSC1) gene in humans encodes a peripheral membrane protein also known as hamartin, TSC, LAM, and KIAA0243. TSC1 complexes with TSC2 (tuberin) and stabilizes it. The TSC1/TSC2 complex inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of eukaryotic translation initiation factor 4E-binding protein 1 (EIF4BP1) and ribosomal protein S6 kinase (S6K1), by negatively regulating signaling in the mammalian target of rapamycin complex 1 (mTORC1). Mutations in the TSC1 gene are associated with the development of tuberous sclerosis.

This product is an affinity-purified IgG antibody that recognizes human TSC1 protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human TSC1 protein.

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  • Cat.#: 28017A, 28017B
  • Target Name: Human TSC1 protein
  • Antigen: Human TSC1 synthetic peptide
  • Specificity: Cross-reacts with mouse TSC1
  • Application: WB, IHC
  • Target Entrez Gene ID: 7248


Recommended antibody concentration (the optimal concentration should be determined empirically):

  • Western blot: 1–5 µg/mL
  • Immunohistochemical techniques: 1–5 µg/mL


Lyophilized: stable 5 years at 2–8°C. In solution: stable 2 years at –20°C.


Lyophilized from an antibody solution containing 1% BSA in PBS and 0.05% NaN3. To use, reconstitute in 1.0 mL H2O (final concentration 100 µg/mL).

Alternative names

Hamartin, TSC, LAM, KIAA0243

Cat. # Product Contents Size Price Units Select
28017A Anti-Human TSC1/Hamartin (T1149) Rabbit IgG Affinity Purify 10 ug $125.00
28017B Anti-Human TSC1/Hamartin (T1149) Rabbit IgG Affinity Purify 100 ug $545.00



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