Reticulocalbin 1 is a calcium-binding protein that belongs to the elongation factor (EF) family and is located in the lumen of the endoplasmic reticulum (ER). In humans, reticulocalbin 1 is encoded by the RCN1 gene. It contains six conserved regions with similarity to a high-affinity calcium-binding motif known as the EF hand. Other functions besides calcium binding have been proposed for reticulocalbin 1 in mouse, but its role is not clear. Expression of reticulocalbin 1 in human endothelial and prostate cancer cell lines demonstrates its localization to the plasma membrane. Reticulocalbin 1 is also known as reticulocalbin 1, EF-hand calcium binding domain; RCN, RCAL, proliferation-inducing gene 20 (PIG20), and FLJ370411.
This product is an affinity-purified IgG antibody that recognizes human reticulocalbin 1 protein. The antibody was raised in mouse using recombinant human reticulocalbin 1 protein and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or immunoprecipitation (IP) of human reticulocalbin 1 protein.