Podoplanin is a type I integral membrane glycoprotein with diverse tissue distribution, expressed at high levels in lung, placenta, and skeletal muscle. In humans, it is encoded by the PDPN gene. The exact function of podoplanin is unknown, but it is thought to be involved in cell migration, motility, and adhesion. Podoplanin is required for normal lung cell proliferation and alveolus formation at birth, and has been proposed as a marker for lung injury. Podoplanin is also known as lung type I cell membrane associated glycoprotein, glycoprotein 36 (GP36), GP38, GP40, T1-alpha, T1A, T1A-2, OTS8, AGGRUS, HT1A-1, and PA2.26.
This product is an affinity-purified IgG antibody that recognizes human podoplanin protein. The antibody was raised in rabbit using a synthetic peptide and can be used for Western blot (WB) detection or immunohistochemical (IHC) detection of human podoplanin protein.