Several antigens specific to lymphatic endothelium have been studied, including LYVE-1, podoplanin, and Prox-1. However, antibodies against these antigens cross-react with other tissues, especially vascular endothelium. The LEC26 antibody is generated using a rapid differential immunization technique. It is specific to lymphatic vessels but does not react with vascular endothelium.
This product is an affinity-purified IgG antibody that recognizes mouse lymphatic vessels. The antibody was raised in rat using a mouse lymphangioma. It can be used for immunohistochemical (IHC) detection of mouse lymphatic vessels.