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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Cancer_and_Inflammation >  Galectin-3

Galectin-3 Detection

Galectin-3 belongs to a family of carbohydrate-binding proteins known as lectins. In humans, it is encoded by the LGALS3 gene and is approximately 30 kDa in size. Galectin-3 has an N-terminal proline-rich tandem repeat domain, which allows it to self-associate, and a single C-terminal carbohydrate recognition domain. It binds beta-galactoside and IgE, and it is required for terminal differentiation of columnar epithelial cells during early embryogenesis. Galectin-3 is involved in a broad range of functions, including innate immunity, chemoattraction, cell adhesion, cell growth and differentiation, T-cell regulation, and apoptosis. Galectin-3 expression is implicated in processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and ventricular remodeling. Elevated levels of galectin-3 are also associated with cancer and inflammation.

Galectin-3 is also known as lectin, galactoside-binding, soluble, 3; carbohydrate-binding protein 35; galactose-specific lectin 3; laminin-binding protein; lectin L-29; Mac-2 antigen; IgE-binding protein; L31; GAL3; MAC2; CBP35; GALBP; GALIG; and LGALS2.

ELISAs for Galectin-3 Detection

This kit is a solid-phase sandwich ELISA using two antibodies that are highly specific to human galectin-3 protein; one is precoated on the ELISA plate and the other is HRP-conjugated. This assay kit can be used to measure soluble human galectin-3 protein in serum, EDTA plasma, cell and tissue lysates, and cell culture supernatants.

Antibodies for Galectin-3 Detection

These products are affinity-purified IgG antibodies that recognize human galectin-3 protein. The antibodies were raised in mouse using recombinant protein, and can be used for Western blot (WB) detection, immunohistochemical (IHC) detection, or flow cytometry (FCM) of human galectin-3 protein.

  At-A-Glance   Documents   Images & Data


Cat. #
(Clone) and Source
Mouse IgG MoAb

Detect: HRP (87B5)
Mouse IgG MoAb
≤0.1% cross‑reactivity with human galectin-1 and mouse galectin-3; 0.21% cross-reactivity with human galectin-4
Galectin‑311100A, BIHC
Mouse IgG MoAb
Galectin‑311102A, BWB
Mouse IgG MoAb

Additional Information

Please see a product's User Manual and Data Sheet for information about storage conditions, product components, and technical specifications. Please see the User Manual to determine kit components. User Manuals and Data Sheets are located under the Documents tab.

Cat. # Product Contents Size Price Units Select
11100A Anti-Human Galectin-3 (38B2) Mouse IgG MoAb 10 ug $113.00
11100B Anti-Human Galectin-3 (38B2) Mouse IgG MoAb 100 ug $499.00
11102A Anti-Human Galectin-3 (87B5) Mouse IgG MoAb 10 ug $113.00
11102B Anti-Human Galectin-3 (87B5) Mouse IgG MoAb 100 ug $499.00
27755A Human Galectin-3 Assay Kit - IBL 96-Well $606.00



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