Glial fibrillary acidic protein (GFAP), a 50 kDa protein, is a major intermediate filament protein in mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in the GFAP gene in humans cause Alexander disease, a very rare, fatal neurodegenerative disease that mostly affects infants and children and results in developmental delay and changes in physical characteristics. GFAP is also known as FLJ45472.
This product is an affinity-purified IgG antibody that recognizes GFAP protein. The antibody was raised in mouse using bovine GFAP, and can be used for immunohistochemical (IHC) detection of GFAP protein.