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Cell Biology & Epigenetics

Products >  Cell_Biology_and_Epigenetics >  Bone_Research >  Dentin_Matrix_Protein1

Dentin Matrix Protein 1 Detection

Dentin matrix protein 1 (DMP1) is an acidic extracellular matrix phosphoprotein that can bind calcium. DMP1 is required for bone and dentin mineralization and is expressed in the cells of bone and teeth. It is thought to play a role in regulating expression of osteoblast-specific genes during osteoblast cell differentiation and is localized to the nucleus in osteoblast precursor cells. In mature osteoblasts, the DMP1 protein is phosphorylated and localized to the extracellular matrix, where it plays a role in forming mineralized matrix. While other constitutively expressed proteins in the extracellular matrix, such as osteopontin and osteocalcin, are expressed in osteoblast cells, DMP1 is expressed in osteocytes, making it a candidate biomarker for osteocyte activity.

Alternative names: dentin matrix protein-1, dentin matrix protein-I, DMP1, DMP-1.

ELISA Kits for Dentin Matrix Protein1 Detection

This kit is a solid-phase sandwich ELISA using two kinds of highly specific antibodies for quantitative detection of rat DMP1 in serum, EDTA plasma, and cell culture supernatant.

Antibodies for Dentin Matrix Protein1 Detection

Anti-Dentin Matrix Protein-I antibody is a rabbit polyclonal antibody raised against the KLH-conjugated peptide (90-111) derived from the N-terminus of rat DMP1. This antibody is intended for the detection of human, mouse, and rat DMP1.

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Cat. #
(Clone) and Source
Dentrin Matrix Protein127363AELISARatCapture:
Rabbit IgG

Detect: HRP
(149) Rabbit IgG 
Does not react with human or mouse Dentin Matrix Protein1
Dentin Matrix Protein1 
Rabbit IgG PoAb 
Cross-reacts with human and mouse Dentin Matrix Protein1

Additional Information

Please see a product's User Manual and Data Sheet for information about storage conditions, product components, and technical specifications. Please see the User Manual to determine kit components. User Manuals and Data Sheets are located under the Documents tab.

Cat. # Product Contents Size Price Units Select
M176 Polyclonal Anti-Dentin Matrix Protein-I (DMP-1) 0.1 mg $421.00
27363A Rat DMP1 Assay Kit - IBL 96-Well $1,011.00



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