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Products >  Cell_Biology_and_Epigenetics >  Epigenetics_Kits >  Immunoprecipitation_Kits >  Chromatin_Immunoprecipitation_ChIP

Chromatin Immunoprecipitation (ChIP) Kits for Epigenetics Studies

Chromatin immunoprecipitation (ChIP) is used to determine the location of DNA binding sites for a particular protein of interest, in order to understand the protein-DNA interactions that occur inside the nucleus of living cells or tissues. ChIP is particularly relevant for epigenetics studies, because DNA-binding proteins play an important role in the regulation of gene expression in healthy cells and organisms and in medically relevant areas such as cancer and immunology.

The EpiXplore Chromatin Immunoprecipitation ChIP kits use magnetic beads and an optimized protocol to make your assay easier— in fact, it can be completed in less than 6 hr. These ChIP kits also include specially formulated buffers which reduce nonspecific DNA pull-down and enhance signal. A DNA purifying resin enables rapid elution of DNA and direct PCR analysis.

  • Use the EpiXplore Chromatin Immunoprecipitation Kit: Protein G to identify protein-DNA interactions via protein G, an immunoglobulin-binding protein.
  • Use the EpiXplore Chromatin Immunoprecipitation (ChIP) Assay Kit: Anti-mouse IgG to identify protein-DNA interactions via anti-mouse beads. This kit has significantly higher affinity for mouse antibodies than protein G, leading to high efficiency pull-down assays when using mouse primary antibodies.

Highly Specific Chromatin Immunoprecipitation

The EpiXplore ChIP Assay Kit yields very specific results. It is possible to perform a successful chromatin immunoprecipitation assay from as few as 1.5 x 105 cells with the EpiXplore ChIP Assay Kit (see Data & Images tab).

At-A-Glance Documents Images & Data

Features

  • Very low nonspecific DNA pull-down
  • Enhanced signal
  • Magnetic beads make ChIP assays easier
  • Choose from Protein G or anti-mouse IgG kits

Applications

  • Chromatin immunoprecipitation (ChIP) assays
  • Identify and understand protein-DNA binding interactions
  • Understand the role of DNA binding proteins in the regulation of gene expression in healthy cells and organisms, and in medically relevant areas such as cancer and immunology

Additional Information

Please see the product's Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Kit Components List to determine kit components. Certificates of Analysis and Kit Components Lists are located under the Documents tab.


 
 
Products
Cat. # Product Package Size Price # of Units Select
632015 EpiXplore™ ChIP Assay Kit: Anti-mouse IgG 24 Assays $629.00
632012 EpiXplore™ ChIP Assay Kit: Protein G 24 Assays $986.00
 

 

Required Products
Cat. # Product Package Size Price # of Units Select
631964 Magnetic Stand 2 x 1.5 mL $42.00
 

 

 


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